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Meningitis
Studies conducted at University of Bern on meningitis recently published
June 24th, 2008
"Treatment of bacterial meningitis caused by Streptococcus pneumoniae is increasingly difficult, because of emerging resistance to antibiotics," scientists in Bern, Switzerland report. "Recombinant Cpl-1, a phage lysin specific for S. pneumoniae, was evaluated for antimicrobial therapy in experimental pneumococcal meningitis using infant Wistar rats," wrote D. Grandgirard and colleagues, University of Bern. The researchers concluded: "A single intracisternal injection (20 mg/kg) of Cpl-1 resulted in a rapid (within 30 min) decrease in pneumococci in cerebrospinal fluid (CSF) by 3 orders of magnitude lasting for 2 h. Intraperitoneal administration of...
Source: TB & Outbreaks Week (2008-06-24)
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