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TB & Outbreaks Week

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Escherichia Coli



New findings reported from Hospital for Sick Children describe advances in Escherichia coli



July 1st, 2008

According to recent research from Toronto, Canada, "Enterohemorrhagic Escherichia coli (EHEC) O157:H7 intimately attaches to intestinal epithelial monolayers and produces attaching and effacing (A/E) lesions. In addition, EHEC infection causes disruptions of intercellular tight junctions, leading to clinical sequelae that include acute diarrhea, hemorrhagic colitis, and the hemolytic-uremic syndrome."

"Current therapy remains supportive since antibiotic therapy increases the risk of systemic complications. This study focused on the potential therapeutic effect of an alternative form of therapy, probiotic Lactobacillus rhamnosus strain GG, to attenuate EHEC-induced...


Source: TB & Outbreaks Week (2008-07-01)

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