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Plague
New plague study findings have been reported from University of Pennsylvania, Medical Department
July 1st, 2008
"Inhaled Yersinia pestis produces a severe primary pneumonia known as proeumonic plague, which is contagious and highly lethal to humans and animals. In this study, we first determined the susceptibility of Y. pestis KIM6 to antimicrobial molecules of the airways," investigators in the United States report. "We found that (i) rat bronchoalveolar lavage fluid (rBALF) effectively killed KIM6 cells growing at 37 degrees C; (ii) the antibacterial components of rBALF were small peptides (< 10 kDa) that included two cationic antimicrobial peptides (CAMPs), the rat cathelicidin rCRAMP, and P-defensin RBD-1; (iii) the human cathelicidin LL-37 killed KIM6 cells as well as...
Source: TB & Outbreaks Week (2008-07-01)
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