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West Nile Virus
New west nile virus study findings recently were published by researchers at Yale University
July 1st, 2008
"Determining how West Nile virus crosses the blood-brain barrier is critical to understanding the pathogenesis of encephalitis. Here, we show that ICAM-1(-/-) mice are more resistant than control animals to lethal West Nile encephalitis," investigators in the United States report. "ICAM-1(-/-) mice have a lower viral load, reduced leukocyte infiltration, and diminished neuronal damage in the brain compared to control animals. This is associated with decreased blood-brain barrier leakage after viral infection," wrote J.F. Dai and colleagues, Yale University. The researchers concluded: "These data suggest that ICAM-1 plays an important role in West...
Source: TB & Outbreaks Week (2008-07-01)
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