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Biochemistry
Scientists at University Hospital release new data on biochemistry
July 1st, 2008
Current study results from the report, 'Molecular characterization of complement Factor I deficiency in two Spanish families,' have been published. According to a study from Madrid, Spain, "Complement Factor I (CFI) is a regulator of the classical and alternative pathways. CFI has enzymatic activity and is able to cleave C3b and C4b." "Homozygous Factor I deficiency is associated with infectious and/or autoimmune diseases. Here we describe the biochemical and genetic characterization in two Spanish families with complete Factor I deficiency. In Family 1, the propositus suffered from several episodes of meningitis for more than a year. Biochemical complement studies...
Source: TB & Outbreaks Week (2008-07-01)
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