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TB & Outbreaks Week

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Hantavirus Therapy



Study findings from Southern Research Institute broaden understanding of hantavirus therapy



July 1st, 2008

Scientists discuss in 'Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus' new findings in hantavirus. "There are no FDA approved drugs for the treatment of hemorrhagic fever with renal syndrome (HFRS), a serious human illnesses caused by hantaviruses. Clinical studies using ribavirin (RBV) to treat HFRS patients suggest that it provides an improved prognosis when given early in the course of disease," investigators in the United States report.

"Given the unique antiviral activity of RBV and the lack of other lead scaffolds, we prepared a diverse series of 3-substituted 1,2,4-triazole-beta-ribosides and...


Source: TB & Outbreaks Week (2008-07-01)

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