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Leishmaniasis Immunology



Research findings from University of Texas, Health Science Center update understanding of leishmaniasis immunology



July 1st, 2008

Researchers detail in 'Pregnancy enhances the innate immune response in experimental cutaneous leishmaniasis through hormone-modulated nitric oxide production,' new data in leishmaniasis. "The maintenance of host defense during pregnancy may depend on heightened innate immunity. We evaluated the immune response of pregnant hamsters during early infection with Leishmania (Viannia) panamensis, a cause of American cutaneous leishmaniasis," scientists in the United States report.

"At 7 days post-infection, pregnant animals showed a lower parasite burden compared with nonpregnant controls at the cutaneous infection site (p=0.0098) and draining lymph node (p=0.02). Resident...


Source: TB & Outbreaks Week (2008-07-01)

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