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TB & Outbreaks Week

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Tuberculosis



Findings from B. Rivassantiago et al in tuberculosis reported



July 8th, 2008

According to a study from Mexico, "Mycobacterium tuberculosis is a facultative intracellular pathogen capable of producing both progressive disease and latent infection. Latent infection is clinically asymptomatic and is manifested only by a positive tuberculin test or a chest radiograph that shows scars or calcified nodules indicative of resolved primary tuberculosis infection."

"In this study, we used a well-characterized model of latent tuberculosis infection in B6D2F1 mice to compare the production of beta-defensin-3 by infected bronchial epithelial cells and macrophages. We demonstrated by immunolectronmicroscopy that M. tuberculosis can actually infect epithelial...


Source: TB & Outbreaks Week (2008-07-08)

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