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Tuberculosis
Studies from C. Flamez and colleagues yield new information about tuberculosis
July 8th, 2008
According to recent research published in the International Journal of Medical Microbiology, "Two-component regulatory systems (2CSs) typically comprise a sensor kinase and a response regulator that, in concert, monitor the concentration of particular extracellular factors and mediate the transcription of specific genes accordingly. As such, 2CSs play an important role in the regulation of bacterial pathogenesis." "On the basis of genome-wide in silico analysis, the Gram-negative enteropathogenic bacterium Yersinia pseudo tuberculosis is thought to encode 24 complete 2CSs. In the present work, we mutated the corresponding 2CS response regulator-encoding genes in...
Source: TB & Outbreaks Week (2008-07-08)
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