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Yersinia
Scientists at Umea University describe research in yersinia
July 8th, 2008
"The bacterial pathogen Yersinia pseudo tuberculosis uses a type III secretion (T3S) system to translocate Yop effectors into eukaryotic cells. Effectors are thought to gain access to the cytosol via pores formed in the host cell plasma membrane," scientists in Umea, Sweden report. "Translocated YopE can modulate this pore formation through its GTPase-activating protein (GAP) activity. In this study, we analysed the role of translocated YopE and all the other known Yop effectors in the regulation of effector translocation. Elevated levels of Yop effector translocation into HeLa cells occurred by YopE-defective strains, but not those defective for other Yop effectors....
Source: TB & Outbreaks Week (2008-07-08)
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