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Encephalitis Vaccines
Reports outline encephalitis vaccines research from University of Texas, Department of Pathology
July 8th, 2008
Fresh data on encephalitis are presented in the report 'Construction and evaluation of a chimeric pseudoinfectious virus vaccine to prevent Japanese encephalitis.' According to recent research published in the journal Vaccine, "Multiple vaccines exist to control Japanese encephalitis (JE), but all suffer from problems. We have developed a new type of flavivirus vaccine, a pseudoinfectious virus (RepliVAX WN) that prevents West Nile virus (WNV)-induced disease." "Here, we describe production of a chimeric RepliVAX (RepliVAX JE) that expresses the JE virus (JEV) prM and E proteins. Our prototype RepliVAX JE replicated poorly in cells, but blind passage produced a...
Source: TB & Outbreaks Week (2008-07-08)
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