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TB & Outbreaks Week

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DNA Research



Research reports from University of Toronto provide new insights into DNA research



July 15th, 2008

"Lsr2 is a small, basic protein present in Mycobacterium and related actinomycetes. Recent studies suggest that Lsr2 is a regulatory protein involved in multiple cellular processes including cell wall biosynthesis and antibiotic resistance," researchers in Toronto, Canada report.

"However, the underlying molecular mechanisms remain unknown. In this article, we performed biochemical studies of Lsr2DNA interactions and structurefunction analysis of Lsr2. Analysis by atomic force microscopy revealed that Lsr2 has the ability to bridge distant DNA segments, suggesting that Lsr2 plays a role in the overall organization and compactness of the nucleoid. Mutational analysis...


Source: TB & Outbreaks Week (2008-07-15)

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