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Life Sciences
Research findings from London School of Hygiene and Tropical Medicine update understanding of life sciences
July 15th, 2008
Fresh data on life sciences are presented in the report 'Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences.' "The reported incidence and mortality of Clostridium difficile-associated disease has increased significantly, which in part is likely to be due to the emergence of a new, highly virulent strain in North America and Europe. This epidemic strain, referred to as BI/NAP1/027, has increased virulence, attributed to overexpression of the two toxin-encoding genes, tcdA and tcdB, which may be due to truncation of the negative regulator (tcdC) by a 1 bp deletion," scientists writing in the Journal of Medical...
Source: TB & Outbreaks Week (2008-07-15)
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