TB & Outbreaks Week
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Bird Flu
New bird flu study findings recently were reported by researchers at Department of Agriculture
July 15th, 2008
According to a study from the United States, "The virulence determinants for highly pathogenic avian influenza viruses (AIVs) are considered multigenic, although the best characterized virulence factor is the hemagglutinin (HA) cleavage site. The capability of influenza viruses to reassort gene segments is one potential way for new viruses to emerge with different virulence characteristics." "To evaluate the role of other gene segments in virulence, we used reverse genetics to generate two H5N1 recombinant viruses with differing pathogenicity in chickens. Single-gene reassortants were used to determine which viral genes contribute to the altered virulence. Exchange of...
Source: TB & Outbreaks Week (2008-07-15)
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