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TB & Outbreaks Week

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Tuberculosis



New tuberculosis data have been reported by S. Pawaria and co-authors



July 22nd, 2008

"The success of Mycobacterium tuberculosis as one of the dreaded human pathogens lies in its ability to utilize different defense mechanisms in response to the varied environmental challenges during the course of its intracellular infection, latency, and reactivation cycle. Truncated hemoglobins trHbN and trHbO are thought to play pivotal roles in the cellular metabolism of this organism during stress and hypoxia," scientists in Chandigarh, India report.

"To delineate the genetic regulation of the M. tuberculosis hemoglobins, transcriptional fusions of the promoters of the glbN and glbO genes with green fluorescent protein were constructed, and their responses were...


Source: TB & Outbreaks Week (2008-07-22)

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