TB & Outbreaks Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB & Outbreaks Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Tuberculosis
Research from University of Washington in the area of tuberculosis published
July 22nd, 2008
According to recent research from the United States, "The response regulator DosR is essential for promoting long-term survival of Mycobacterium tuberculosis under low oxygen conditions in a dormant state and may be responsible for latent tuberculosis in one-third of the world's population. Here, we report crystal structures of full-length. p unphosphorylated DosR at 2.2 angstrom resolution and its C-terminal DNA-binding domain at 1.7 angstrom resolution." "The full-length DosR structure reveals several features never seen before in other response regulators. The N-terminal domain of the full-length DosR structure has an unexpected (beta alpha)(4) topology instead of...
Source: TB & Outbreaks Week (2008-07-22)
|
