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Tuberculosis
Research on tuberculosis described by V. Leiro and colleagues
July 22nd, 2008
According to recent research published in the journal Liver International, "Genetic variations in enzymes of isoniazid metabolism confer an increased risk for antituberculosis drug-induced hepatotoxicity in Asian populations. The present study was aimed at investigating the possible association of antituberculosis drug-induced hepatotoxicity with polymorphisms at the glutathione S-transferase (GST) gene in a Caucasian population." "A prospective case-control study was nested in a cohort of patients with active tuberculosis who were treated with a combination of isoniazid, rifampicin and pyrazinamide. Cases constituted patients with antituberculosis drug-induced...
Source: TB & Outbreaks Week (2008-07-22)
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