Immunology
Reports from University of Texas, Health Science Center highlight recent research in immunology
Published in TB and Outbreaks Week, July 22nd, 2008
Researchers detail in 'An age-old paradigm challenged: old baboons generate vigorous humoral immune responses to LcrV, a plague antigen,' new data in immunology. According to a study from the United States, "Immune senescence in the elderly results in decreased immunity with a concomitant increase in susceptibility to infection and diminished efficacy of vaccination. Nonhuman primate models have proven critical for testing of vaccines and therapeutics in the general population, but a model using old animals has not been established."
"Toward that end, immunity to LcrV, a protective Ag from Yersinia pestis, was tested in young and old baboons. Surprisingly, there was no...
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