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Influenza
Research from Children's Hospital reveals new findings on influenza
July 29th, 2008
"If highly pathogenic H5N1 influenza viruses acquire affinity for human rather than avian respiratory epithelium, will their susceptibility to neuraminidase (NA) inhibitors (the likely first line of defense against an influenza pandemic) change as well' Adequate pandemic preparedness requires that this question be answered. We generated and tested 31 recombinants of A/Vietnam/1203/04 (H5N1) influenza virus carrying single, double, or triple mutations located within or near the receptor binding site in the hemagglutinin (HA) glycoprotein that alter H5 HA binding affinity or specificity," scientists in the United States report. "To gain insight into how combinations of HA...
Source: TB & Outbreaks Week (2008-07-29)
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