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TB & Outbreaks Week

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Tuberculosis



New tuberculosis findings from K.C. Chang and co-authors described



July 29th, 2008

According to recent research from Wanchai, People's Republic of China, "Relatively little is known about the hepatotoxicity of pyrazinamide. We compared continuation-phase regimens incorporating pyrazinamide, isoniazid, and/or rifampin with those containing isoniazid and rifampin to evaluate the hepatotoxicity of pyrazinamide."

"Cohort and nested case-control analyses were conducted on a cohort of 3,007 patients with active tuberculosis (TB) managed at government chest clinics under a TB control program with treatment started from January 1 through June 30, 2001. Cases included all patients with probable hepatotoxicity from 12 or more weeks after starting treatment....


Source: TB & Outbreaks Week (2008-07-29)

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