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DNA Vaccines
New DNA vaccines study findings have been reported from Catholic University, Institute of Microbiology
July 29th, 2008
New investigation results, 'Evaluation of the anti-tuberculosis activity generated by different multigene DNA vaccine constructs,' are detailed in a study published in Microbes and Infection. "Development of multigenic constructs expressing Mycobacterium tuberculosis (Mtb) antigens may be a strategy to obtain improved DNA vaccines against tuberculosis (TB). Several multigenic constructs expressing two or three Mtb antigens as fusion proteins were developed, both as tPA-and ubiquitin-fusion proteins," investigators in Rome, Italy report. "To demonstrate proper protein expression and intracellular turnover all multiantigens were tagged with the HA epitope...
Source: TB & Outbreaks Week (2008-07-29)
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