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TB & Outbreaks Week

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Plague



Study data from University of Turin update knowledge of plague



August 5th, 2008

"A rapid diagnostic test (RDT) that detects Yersinia pestis F1 antigen was applied to 28 putative plague victims exhumed from seven burial sites in southeastern France dating to the 16th-18th centuries. Yersinia pestis F1 antigen was detected in 19 of the 28 (67.9%) samples," researchers in Turin, Italy report.

"The 27 samples used as negative controls yielded negative results. Soil samples taken from archeological sites related to both positive and negative samples tested negative for F1 antigen. The detection threshold of the RDT for plague (0.5 ng/ml) is sufficient for a preliminary retrospective diagnosis of Y pestis infection in human remains. The high specificity...


Source: TB & Outbreaks Week (2008-08-05)

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