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Tuberculosis
Research from Nanchang University reveals new findings on tuberculosis
August 5th, 2008
According to a study from Nanchang, People's Republic of China, " Isocitrate lyase (ICL) was previously demonstrated to play a pivotal role in the intracellular metabolism of Mycobacterium tuberculosis (MTB). Presently several lines of evidence suggest that ICL from MTB (MTB-ICL) may play some roles in the interaction between MTB and host macrophage." "However, there has been no research on the interaction between MTB-ICL and host macrophage. MTB-icl and M. smegmatis (MS)-icl genes were amplified by polymerase chain reaction (PCR) and cloned into the E coli-mycobacterium shuttle plasmid pUV15 to obtain recombinant shuttle plasmids pMTB-icl and pMS-icl. Following...
Source: TB & Outbreaks Week (2008-08-05)
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