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Dengue Fever
Research from R. Soundravally and co-authors yields new data on dengue fever
August 12th, 2008
"Background and Aims The polymorphic transporter associated with antigen processing (TAP)1 and TAP2 genes encode subunits of the transporter that delivers peptides to the human leukocyte antigen class I molecules. Because the polymorphism of the TAP genes has been shown to affect peptide transport, it has been suggested that TAP genes are potential regulators of the immune response," scientists writing in the Journal of Clinical Immunology report. "We recently reported that TAP1 gene polymorphism is associated with severe dengue infection. This study was carried out to elucidate whether TAP2 polymorphisms are involved in diverse pathogenesis of dengue infection....
Source: TB & Outbreaks Week (2008-08-12)
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