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Hemorrhagic Fever
Studies from I. Andersson et al add new findings in the area of hemorrhagic fever
August 12th, 2008
"As a first line of defence against virus infection, mammalian cells elicit an innate immune response, characterized by secretion of type I interferons and the up-regulation of interferon stimulated genes. Many viruses down-regulate the innate immune responses in order to enhance their virulence," scientists in Solna, Sweden report. "Crimean-Congo hemorrhagic fever virus (CCHFV), a Nairovirus of the family Bunyaviridae is the causative agent of severe hemorrhagic fever in humans with high mortality. Knowledge regarding the innate immune response against CCHFV is most limited. Interestingly, in this study it is shown that replicating CCHFV delays substantially the IFN...
Source: TB & Outbreaks Week (2008-08-12)
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