TB & Outbreaks Week
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Life Sciences
Data on life sciences published by researchers at Oregon Health & Science University
August 12th, 2008
According to recent research from the United States, "West Nile virus (WNV) has been the leading cause of viral encephalitis in the United States since 1999. The endocytic processes involved in the internalization of infectious WNV by various cell types are not well characterized, and the involvement of cholesterol-rich membrane microdomains, or lipid rafts, in the life cycle of WNV has not been investigated previously." "In this study, we found that the depletion of cellular cholesterol levels by brief treatment with methyl-beta-cyclodextrin resulted in a 100-fold reduction of the titers of infectious WNV released into the culture supernatant, as well as a reduction in...
Source: TB & Outbreaks Week (2008-08-12)
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