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TB & Outbreaks Week

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Meningitis



Study data from R. Maruvada and co-authors update knowledge of meningitis



August 12th, 2008

"Escherichia coli K1 and Group B Streptococcus (GBS) are the most common bacteria that cause meningitis during the neonatal period. Complement, the first line of defence in the host, acts on these bacteria to opsonize with various components of complement for subsequent presentation to phagocytes," researchers in the United States report.

"To counteract these opsonization effects, E. coli and GBS bind to the complement regulators C4 binding protein and Factor H, respectively. Nonetheless, the deposition of complement components on these two bacteria from neonatal serum and their effect on the host cell interaction is unclear. Here we demonstrated that the deposition of...


Source: TB & Outbreaks Week (2008-08-12)

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