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TB & Outbreaks Week

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Tuberculosis



Reports from C.T.D. Price et al highlight recent research in tuberculosis



August 19th, 2008

According to a study from the United States, "Mycobacterium tuberculosis maintains a large genetic capacity necessary for growth in different environments during infection and survival upon aerosol transmission to new hosts. Screening for bacterial RNAs produced in response to host interactions produced candidate lists where we noted proXVWZ, annotated as encoding a putative glycine betaine or proline transporter."

"As high surface-to-volume ratios make bacterial cells particularly vulnerable to changes in water availability, we investigated the contributions of this transporter to the ability of M. tuberculosis to colonize macrophages. An H37Rv proXVWZ mutant was...


Source: TB & Outbreaks Week (2008-08-19)

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