TB & Outbreaks Week
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Bacillus Calmette-Guerin Vaccines
Research in the area of Bacillus calmette-guerin vaccines reported from University of Colorado, Medical Department
August 19th, 2008
According to recent research from the United States, "Mycobacterium tuberculosis is the causative agent of tuberculosis, a disease that affects one-third of the world's population. The sole extant vaccine for tuberculosis is the live attenuated Mycobacterium bovis bacillus Calmette-Guerin (BCG)." "We examined 13 representative BCG strains from around the world to ascertain their ability to express DosR-regulated dormancy antigens. These are known to be recognized by T cells of M. tuberculosis-infected individuals, especially those harboring latent infections. Differences in the expression of these antigens could be valuable for use as diagnostic markers to distinguish...
Source: TB & Outbreaks Week (2008-08-19)
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