Leishmaniasis
Researchers from Banaras Hindu University discuss findings in leishmaniasis
Published in TB and Outbreaks Week, August 26th, 2008
"The aim of the present study was to compare the efficacy of a nano form of amphotericin B deoxycholate with that of conventional amphotericin B deoxycholate for the treatment of visceral leishmaniasis. We have formulated nanoparticles (10-20 nM) from amphotericin B deoxycholate (1-2 mc M) by applying high-pressure (150 argon) milling homogenization and have tested their efficacy in a J774A cell line and in hamsters," scientists in Varanasi, India report.
"Parasite survival and tissue burden in spleen were evaluated for nano-amphotericin B and conventional amphotericin B. Both nano-amphotericin B and conventional amphotericin B were injected intraperitoneally at 5 mg/kg...
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