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Mycobacteria
Studies conducted at University of Murcia on mycobacteria recently published
August 26th, 2008
Researchers in Murcia, Spain conducted a study "To determine the composition of polar glycopeptidolipids (pGPLs) of Mycobacterium simiae and, particularly, those of 'habana' strains, in a search for specific markers given the immunogenic potential of 'habana' TMC 5135 in experimental tuberculosis. pGPLs were determined in free lipid extracts using electrospray ionization-ion trap-mass spectrometry (ESI-IT-MS), working in both negative- and positive-ion mode." "In the case of TMC 5135, the presence of the previously characterized GPL-II (containing 2,4-di-O-CH3 glucuronic acid as distal sugar in the oligosaccharide antigenic moiety) and GPL-III (containing 4-O-CH3...
Source: TB & Outbreaks Week (2008-08-26)
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