TB & Outbreaks Week
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Antibiotics
New antibiotics data have been reported by P.L. Hinkson and co-authors
August 26th, 2008
"Clostridium difficile-associated diarrhea (CDAD) is caused by the toxins the organism produces when it overgrows in the colon as a consequence of antibiotic depletion of normal flora. Conventional antibiotic treatment of CDAD increases the likelihood of recurrent disease by again suppressing normal bacterial flora," researchers in the United States report. "Tolevamer, a novel toxin-binding polymer, was developed to ameliorate the disease without adversely affecting normal flora. In the current study, tolevamer was tested for its ability to neutralize clostridial toxins produced by the epidemic BI/027 strains, thereby preventing toxin-mediated tissue culture cell...
Source: TB & Outbreaks Week (2008-08-26)
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