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Tuberculosis
Research conducted at University of Oregon has provided new information about tuberculosis
August 26th, 2008
"Mycobacteria, including persistent pathogens like Mycobacterium tuberculosis, have an unusual membrane structure in which, outside the plasma membrane, a nonfluid hydrophobic fatty acid layer supports a fluid monolayer rich in glycolipids such as trehalose 6,6'-dimycolate (TDM; cord factor). Given the abilities of mycobacteria to survive desiccation and trehalose in solution to protect biomolecules and whole organisms during freezing, drying, and other stresses, we hypothesized that TDM alone may suffice to confer dehydration resistance to the membranes of which it is a constituent," scientists writing in the Biophysical Journal report. "We devised an...
Source: TB & Outbreaks Week (2008-08-26)
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