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Tuberculosis
Scientists at University of Athens describe research in tuberculosis
August 26th, 2008
"Treatment with tumor necrosis factor (TNF) antagonists in patients with rheumatic diseases has been associated with increased rates of tuberculosis due to reactivation of latent Mycobacterium tuberculosis (MTb) infection (LTBI). Diagnosis of LTBI is based mainly on the tuberculin skin test (TST), which has certain limitations," scientists in Athens, Greece report. "We compared the TST with an enzyme-linked immunospot interferon-gamma(IFN-gamma) release assay (Elispot; T SPOT (R) TB) for the diagnosis of LTBI in 70 patients with various rheumatic diseases starting treatment with anti-TNF agents. All patients underwent a standard initial evaluation for LTBI including...
Source: TB & Outbreaks Week (2008-08-26)
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