TB & Outbreaks Week
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Enzyme Research
Reports outline enzyme research research from T. Chopra and colleagues
September 2nd, 2008
"In recent years, remarkable versatility of polyketide synthases (PKSs) has been recognized; both in terms of their structural and functional organization as well as their ability to produce compounds other than typical secondary metabolites. Multifunctional Type I PKSs catalyze the biosynthesis of polyketide products by either using the same active sites repetitively (iterative) or by using these catalytic domains only once ( modular) during the entire biosynthetic process," scientists writing in the journal Plos Biology report. "The largest open reading frame in Mycobacterium tuberculosis, pks12, was recently proposed to be involved in the biosynthesis of...
Source: TB & Outbreaks Week (2008-09-02)
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