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TB & Outbreaks Week

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Influenza



New findings reported from L.M. Chen and co-authors describe advances in influenza



September 2nd, 2008

According to recent research published in the journal Plos Pathogens, "The segmented structure of the influenza virus genome plays a pivotal role in its adaptation to new hosts and the emergence of pandemics. Despite concerns about the pandemic threat posed by highly pathogenic avian influenza H5N1 viruses, little is known about the biological properties of H5N1 viruses that may emerge following reassortment with contemporary human influenza viruses."

"In this study, we used reverse genetics to generate the 63 possible virus reassortants derived from H5N1 and H3N2 viruses, containing the H5N1 surface protein genes, and analyzed their viability, replication...


Source: TB & Outbreaks Week (2008-09-02)

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