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TB & Outbreaks Week

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Legionnaire Disease



Research conducted at University of Lyon has provided new information about legionnaire disease



September 2nd, 2008

In this recent report published in the journal Intensive Care Medicine, researchers in Lyon, France conducted a study "To examine the effect of intratracheal heparin instillation on Legionella pneumophila-related acute lung injury (ALI) and systemic dissemination. Prospective, controlled experimental study."

"University research laboratory. A/J mice received 5 mu g of sulfated heparin intratracheally co-instilled with 106 or 108 colony-forming units (CFU) of a virulent isolate of L. pneumophila. ALI was assessed in control groups (PBS and PBS-heparin) and on days 1, 2 and 3 post-infection, in terms of the lung wet-to-dry (W/D) weight ratios and of lung...


Source: TB & Outbreaks Week (2008-09-02)

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