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Plague
Research on plague reported by scientists at University of California
September 2nd, 2008
"Yersinia pestis, the agent of bubonic plague, evolved from the enteric pathogen Yersinia pseudo tuberculosis within the past 20,000 years. Because ancestor and descendant both exist, it is possible to infer steps in molecular evolution by direct experimental approaches. The Y. pestis life cycle includes establishment of a biofilm within its vector, the flea. Although Y. pseudotuberculosis makes biofilms in other environments, it fails to do so in the insect," scientists in the United States report. "We show that rcsA, a negative regulator of biofilms that is functional in Y. pseudotuberculosis, is a pseudogene in Y. pestis. Replacement of the pseudogene with the...
Source: TB & Outbreaks Week (2008-09-02)
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