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NIH/National Institute of Allergy and Infectious Diseases



Leishmaniasis parasites evade death by exploiting the immune response to sand fly bites



September 2nd, 2008

Cutaneous leishmaniasis, a disease characterized by painful skin ulcers, occurs when the parasite Leishmania major, or a related species, is transmitted to a mammalian host by the bite of an infected sand fly. In a new study from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, scientists have discovered L. major does its damage by not only evading but also by exploiting the body's wound-healing response to sand fly bites, as reported in the August 15 issue of Science.

"This work changes the textbook picture of the lifecycle of the leishmaniasis parasite, identifying the inflammatory cell known as the...


Source: TB & Outbreaks Week (2008-09-02)

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