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TB & Outbreaks Week

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Tuberculosis



Researchers from University of Pittsburgh describe findings in tuberculosis



September 2nd, 2008

According to recent research from the United States, "Successful treatment of human tuberculosis requires 6-9 months' therapy with multiple antibiotics."

"Incomplete clearance of tubercle bacilli frequently results in disease relapse, presumably as a result of reactivation of persistent drug-tolerant Mycobacterium tuberculosis cells, although the nature and location of these persisters are not known. In other pathogens, antibiotic tolerance is often associated with the formation of biofilms - organized communities of surface-attached cells - but physiologically and genetically defined M. tuberculosis biofilms have not been described," wrote A.K. Ojha and colleagues,...


Source: TB & Outbreaks Week (2008-09-02)

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