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Lung Disease

New data from H.Y. Park et al illuminate research in lung disease

Published in TB and Outbreaks Week, September 9th, 2008

"The pathway involving interferon-gamma and interleukin (IL)-12 plays an important role in host defense against mycobacterial infections. Recent studies have indicated that IL-12 receptor beta 1 (IL-12R beta 1) gene polymorphisms are associated with susceptibility to pulmonary tuberculosis," scientists in Seoul, South Korea report.

"However, there have been no reports of an association between IL-12R beta 1 gene polymorphism and lung disease caused by nontuberculous mycobacteria (NTM). The present study involved 128 patients with the nodular bronchiectatic form of NTM lung disease (75 patients with Mycobacterium avium-intracellulare complex infection and 53 patients...

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