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West Nile Virus
Research from L. Sebastian and co-authors yields new data on west nile virus
September 9th, 2008
"During the early and mid part of 20(th) century, several reports described the therapeutic effects of N-methylisatin-beta-Thiosemicarbazone (MIBT) against pox viruses, Maloney leukemia viruses and recently against HIV. However, their ability to inhibit flavivirus replication has not been investigated," scientists in Bangalore, India report. "Hence the present study was designed to evaluate the antiviral activity of 14 MIBT derivatives against Flaviviruses that are prevalent in India such as Japanese Encephalitis Virus (JEV), Dengue-2 (Den-2) and West Nile viruses (WNV). Amongst the fourteen Mannich bases of MIBT derivatives tested one compound-SCH 16 was able to...
Source: TB & Outbreaks Week (2008-09-09)
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