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Bird Flu
Study data from University of St. Andrews, Center for Biomolecular Sciences update understanding of bird flu
September 9th, 2008
Investigators publish new data in the report 'Structure of an avian influenza A virus NS1 protein effector domain.' According to recent research published in the journal Virology, "Influenza A virus NS1 protein is a multifunctional virulence factor. Here, we report a crystal structure for the NS1 effector domain of avian influenza virus A/Duck/Albany/76." "Comparison of this structure with that reported for a human strain shows both proteins share a common monomer conformation, albeit with subtle differences. Strikingly, our data reveal a novel helix-helix dimeric interface between monomers of the avian NS1 protein, which is also found in the human NS1 crystal...
Source: TB & Outbreaks Week (2008-09-09)
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