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Enzyme Research
Scientists at Technical University Munchen, Research Department describe research in enzyme research
September 9th, 2008
Investigators publish new data in the report 'Biosynthesis of isoprenoids: studies on the mechanism of 2C-methyl-D-erythritol-4-phosphate synthase.' "2C-Methyl-D-erythritol-4-phosphate synthase, encoded by the ispC gene (also designated dxr), catalyzes the first committed step in the nonmevalonate isoprenoid biosynthetic pathway. The reaction involves the isomerization of 1-deoxy-D-xylulose 5-phosphate, giving a branched-chain aldose derivative that is subsequently reduced to 2C-methyl-D-erythritol 4-phosphate," scientists writing in the FEBS Journal report. "The isomerization step has been proposed to proceed as an intramolecular rearrangement or a...
Source: TB & Outbreaks Week (2008-09-09)
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