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TB & Outbreaks Week

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Immunization



Research data from Clinical Research Institute of Montreal update understanding of immunization



September 9th, 2008

Researchers detail in 'The H5N1 influenza variant Fujian-like hemagglutinin selected following vaccination exhibits a compromised furin cleavage : neurological Consequences of highly pathogenic Fujian H5N1 strains,' new data in immunization. According to recent research from Montreal, Canada, "The outbreak of H5N1 avian influenza strains infectious to human has dire neurological and pathological consequences. This led to the massive vaccination of host poultry, resulting in a Fujian-like variant (vFJ) resistant to immunization with two mutations at the furin-processing site of hemagglutinin: loss of the P2 Lys and P9 substitution of Gln to Leu within the cleavage site."

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Source: TB & Outbreaks Week (2008-09-09)

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