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TB & Outbreaks Week

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Life Sciences



Data on life sciences discussed by researchers at University of Sevilla



September 9th, 2008

Data detailed in 'Docking, synthesis, and NMR studies of mannosyl trisaccharide ligands for DC-SIGN lectin' have been presented. According to recent research from Seville, Spain, "DC-SIGN, a lectin, which presents at the surface of immature dendritic cells, constitutes nowadays a promising target for the design of new antiviral drugs. This lectin recognizes highly glycosylated proteins present at the surface of several pathogens such as HIV, Ebola virus, Candida albicans, Mycobacterium tuberculosis, etc."

"Understanding the binding mode of this lectin is a topic of tremendous interest and will permit a rational design of new and more selective ligands....


Source: TB & Outbreaks Week (2008-09-09)

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