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Life Sciences
Reports outline life sciences research from School of Pharmacy
September 9th, 2008
Data detailed in 'Differential expression of the polysialyl capsule during blood-to-brain transit of neuropathogenic Escherichia coli K1' have been presented. According to recent research published in the journal Microbiology, "Escherichia coli K1 isolates synthesize a polysialic acid (polySia) capsule, are components of the adult gastrointestinal microbiota and may cause lethal bacteraemia and meningitis if acquired maternally by newborn infants. We used a neonatal rat pup K1 infection model to establish that prompt administration of a selective capsule depolymerase reverses the bacteraemic state and prevents death of almost all pups." "In untreated...
Source: TB & Outbreaks Week (2008-09-09)
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