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TB & Outbreaks Week

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Emerging Infectious Diseases



Study data from L. Boumgharbourtchai and co-authors update knowledge of emerging infectious diseases



September 16th, 2008

"Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L)," investigators in Caen, France report.

"The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2'-phosphotransferase that inactivates macrolides," wrote L. Boumgharbourtchai and colleagues.

The researchers concluded: "Emergence of the mph(A) gene in S. sonnei may limit usefulness of azithromycin for treatment of shigellosis."

Boumgharbourtchai and colleagues published their study in Emerging Infectious Diseases (Macrolide-resistant Shigella sonnei. Emerging Infectious...


Source: TB & Outbreaks Week (2008-09-16)

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