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TB & Outbreaks Week

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Gene Therapy



New gene therapy research has been reported by scientists at Ewha Womans University



September 16th, 2008

"Since the first use of streptomycin as an effective antibiotic drug in the treatment of tuberculosis, aminoglycoside antibiotics have been widely used against a variety of bacterial infections for over six decades. However, the pathways for aminoglycoside biosynthesis still remain unclear, mainly because of difficulty in genetic manipulation of actinomycetes producing this class of antibiotics," scientists in Seoul, South Korea report.

"Gentamicin belongs to the group of 4,6-disubstituted aminoglycosides containing a characteristic core aminocyclitol moiety, 2-deoxystreptamine (2-DOS), and the recent discovery of its biosynthetic gene cluster in Micromonospora...


Source: TB & Outbreaks Week (2008-09-16)

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