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TB & Outbreaks Week

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Life Sciences



New findings from Federal University of Minas Gerais in the area of life sciences published



September 23rd, 2008

According to recent research from Belo Horizonte, Brazil, "The toxicity and antileishmanial effectiveness of a novel liposome formulation of meglumine antimoniate in mongrel dogs with visceral leishmaniasis (VL) obtained from a region where VL is endemic in Brazil have been investigated. Groups of 12 animals received by the intravenous route four doses (with 4-day intervals) of either liposomal meglumine antimoniate (group I [GI], 6.5 mg Sb/kg of body weight/dose), empty liposomes (GII), or isotonic saline (GIII)."

"Evaluation of markers of hematopoietic, hepatic, and renal functions before and just after treatment showed no significant change. On the other hand,...


Source: TB & Outbreaks Week (2008-09-23)

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